for Aug 30, 2021 through Sep 05, 2021
If I could message, I would start with history of infectious diseases, how the immune system works, how the vaccines are working well if you understand the immune system, and how (like Europe) we can get back to normal life with vaxhttps://t.co/lJj32sfmpq
— Monica Gandhi MD, MPH (@MonicaGandhi9) September 3, 2021
Here’s the systematic review that I referenced, from Clinical Infectious Diseases published in June. As the authors concluded, after reviewing findings from 10 randomized controlled trials, “...ivermectin is not a viable option to treat #covid19.” https://t.co/DlRqR8NI3p https://t.co/i1mGMOAtZG
— Leana Wen, M.D. (@DrLeanaWen) September 2, 2021
🆕💥@jac_amr
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 1, 2021
The first study to evaluate the clinical impact & safety of early procalcitonin-guided antimicrobial stewardship in patients with #COVID19 pneumonia in comparison with a standard of care
D/C Abx when PCT<=0.25ng/ml #IDTwitter #medtwitter https://t.co/5uNniO685Y
🆕💥💥Pharmacokinetic/pharmacodynamic analysis of oral fosfomycin against Enterobacterales, Pseudomonas aeruginosa and Enterococcus spp. in an in vitro bladder infection model: impact on clinical breakpoints @BradSpellberg #IDTwitter https://t.co/roFRysWFdk
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 2, 2021
With the limited oral antibiotics options for treatment of ESBL infections, this option is an attractive one!
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 30, 2021
The addition of amoxicillin/clavulanate restored susceptibility for cefixime and cefpodoxime in 97.2% and 55.4% of isolates #IDTwitter https://t.co/IFlGB9kpzA
🆕💥RCT @jac_amr @peripatetical
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 31, 2021
Et Al
The impact of early antimicrobial stewardship team "review 48 h"
intervention on appropriateness of antimicrobial therapy in patients with Medical Emergency Team calls for suspected sepsis #IDTwitter https://t.co/PcxAVpNvwj pic.twitter.com/YpCSYwFz09
WHY does IDSA not include testing as a layer to keep kids in school!
— Michael Mina (@michaelmina_lab) August 30, 2021
Tests are our eyes on the virus
Quarantine/outbreaks result from not knowing whos infectious - an information problem
Rapid Tests give that information!
Test to stay.https://t.co/so8f4aUiuO via @IDSAInfo pic.twitter.com/br2neUb1Tw
The key implication of this study is NOT that antibody (Ab) responses to Moderna > Pfizer so 🪄🦄 let's boost Pfizer
— Tim Lahey, MD, MMSc (@TimLaheyMD) September 4, 2021
No. It's that Ab responses were different despite equivalent efficacy vs disease
The key implication:⚠️ Don’t over-interpret Ab data⚠️https://t.co/HeBIqeQAuZ
From one of the smartest infectious disease docs in Canada:
— Justin Morgenstern (@First10EM) September 5, 2021
"We have come to learn over the past 18 months that virus-containing aerosols are a dominant method of COVID-19 transmission"https://t.co/taGtZ8i4eA
But our hospitals deny this and refuse to protect our patients
DNA analysis of teeth scrapings from bear skulls dating to 1842 revealed that antibiotic-resistant bacteria in bears spiked after introduction of #antibiotics in Sweden in 1951.
— MicrobesInfect (@MicrobesInfect) September 5, 2021
“When humans start using antibiotics, antibiotics get into the environment”https://t.co/HSQ2vdMfAQ
Article I wrote for @leaps_org
— Monica Gandhi MD, MPH (@MonicaGandhi9) September 2, 2021
-How history of infectious diseases teaches us only immunity can get us through pandemic (influenza 1918, measles, smallpox)
-How immune system works: antibodies wane but B/T cells there
-Why global vax equity paramounthttps://t.co/lJj32sfmpq
UTI may ⬆️ the risk of developing delirium what about asymptomatic bacteriuria (ASB)?
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 30, 2021
The is the first meta-analysis of the associations of delirium with UTI and ASB in adults aged 65 & older
Only delirium and UTI were found to be significantly associated https://t.co/iyqokvrvSf
Dr. Anu Wadhwa, a pediatric infectious diseases staff physician at the Hospital for Sick Children in Toronto who has been treating and studying children with long-COVID, says the virus can set kids back for months. https://t.co/KmK7ioeDZz
— CBC Toronto (@CBCToronto) September 5, 2021
🆕💥prospective cluster-randomized crossover study#CID @IDSAInfo @rebsmoe et Al
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 30, 2021
Impact of Antibiotic Stewardship Rounds in the Intensive Care Setting #IDTwitter #medtwitter #TwitteRx https://t.co/111fEJhTb9
A new study @ICHEJournal @SHEA_EPI from CDC is the first comprehensive look at the impact of COVID-19 on the incidence of healthcare-associated infections
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 2, 2021
Significant ⬆️ in the national SIRs for CLABSI, CAUTI, VAE, MRSA bacteremia were observed in 2020 https://t.co/DVCq7Bxb8b pic.twitter.com/bAHFkiV1bP
🆕💥 #ofid
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 30, 2021
Vancomycin or Daptomycin for Outpatient Parenteral Antibiotic Therapy: Does It Make a Difference in Patient Satisfaction?
More satisfied with Dapto or Vanco? What do you think #IDTwitter https://t.co/Ual1sPs8Lh
🆕💥💥Worldwide Retrospective study : WHO global antimicrobial resistance surveillance for Neisseria gonorrhoeae 2017–18
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 3, 2021
⛔Worrisome ⛔: the annual proportion of decreased susceptibility or resistance across countries was 0–21% to ceftriaxone #IDTwitter https://t.co/pvGNqAloKF pic.twitter.com/1qOnmqCx8w
🆕💥 #AAC @ASMicrobiology by @jasonroberts_pk et Al
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 30, 2021
Population pharmacokinetics of piperacillin and tazobactam in critically ill patients receiving extracorporeal membrane oxygenation (an ASAP ECMO study) #IDTwitter #medtwitter #TwitteRx https://t.co/yTgdAb2rAL
🆕💥💥@LancetRespirMed COV-BARRIER RCT
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 1, 2021
Baricitinib did not improve composite 1 endpoint of progression to NIV,high-flow O2, IMV, or death
But in addition to SOC (eg dexa) it ⬇️ 28-day all-cause mortality by 38·2%
1 additional death was prevented per 20 pts https://t.co/tz1LICKoaB pic.twitter.com/ziMM4RpUAv
Covid-19 vaccines continue to offer strong protection against severe illness and hospitalization, according to research on more than 1,000,000 people published Wednesday in The Lancet Infectious Diseases. https://t.co/FR2tZm7sqo
— NBC News (@NBCNews) September 2, 2021
Covid-19 vaccines continue to offer strong protection against severe illness and hospitalization, according to research on more than 1,000,000 people published Wednesday in The Lancet Infectious Diseases. https://t.co/vG5HWXrcu2
— MSNBC (@MSNBC) September 2, 2021
By showing dendritic cells partake in a “division of labor” when responding to a promising vaccine vector, a new study from @scisignal may inform the design of new #vaccines for infectious diseases and cancer. https://t.co/1WZy00jI3y pic.twitter.com/RurrDFyE2R
— Science Magazine (@ScienceMagazine) September 3, 2021
A coronavirus variant of interest known as #MuVariant is not an “immediate threat” to the US, says Anthony Fauci.
— MicrobesInfect (@MicrobesInfect) September 3, 2021
The variant is “not at all even close to being dominant,” as the #DeltaVariant remains the cause of over 99% of cases in the country.https://t.co/ZYAmI9AKGS #Mu
🆕💥Small retrospective cohort study Penicillin Vs. anti-staphylococcal beta-lactams for penicillin-susceptible Staphylococcus aureus blood stream infections #PSSA
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 31, 2021
No difference in mortality, awaiting @snap_trial @Josh_S_Davis @syctong @DrToddLee https://t.co/XPx7zo7N2a
A Review published in @NatRevDrugDisc discusses the principles of mRNA vaccine design, synthesis and delivery, and assesses recent progress and key issues in the development of mRNA vaccines for a range of infectious diseases. https://t.co/BkhlL9FrH5 pic.twitter.com/bdJoFuVFn7
— Nature Portfolio (@NaturePortfolio) September 2, 2021
Dr. Monica Gandhi – Infectious Diseases Expert – LIVE on #DoseOfDrdrew https://t.co/b0XNzuWT6p
— Dr. Drew (@drdrew) September 1, 2021
Very Important! We need more studies
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 2, 2021
Coronavirus vaccines cut risk of long Covid
The study @TheLancetInfDis
found that the odds of having symptoms for 28 days or more after post-vaccination infection were approximately halved by having two vaccine doses. https://t.co/QtTq2VGStG
A large 🇪🇸 retrospective study @c_garciavidal
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 2, 2021
Remdesivir was associated with 62% reduced odds of death Vs standard-of-care treatment, but the difference was observed mainly among patients with ≤6 days of symptoms before being admitted to the hospital https://t.co/sk7vOaenUr pic.twitter.com/X0Dc40ilGc
BNT162b2 vaccine booster dose protection: A nationwide study from Israel https://t.co/3uBPnD51Dl 12 days or more after the booster dose we found an 11.4-fold (95% CI: [10.0, 12.9]) ⬇️in the RR of confirmed infection, and a >10-fold ⬇️in the relative risk of severe illness.
— Carlos del Rio (@CarlosdelRio7) August 31, 2021
Atlanta archbishop says no to religious exemptions for COVID-19 vaccine @ajc https://t.co/du2YlAUEv7
— Carlos del Rio (@CarlosdelRio7) September 4, 2021
Ongoing RCTs: Cefazolin Vs Antistaphylococcal penicillins eg :Cloxacillin
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) September 3, 2021
✨CLOCEBA 🇫🇷 Recruiting
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in MSSA Bacteremia https://t.co/Ibe1nj1j08
✨ @snap_trial 🇦🇺 not recruiting yet#IDTwitter #medtwitter #TwitteRx https://t.co/zy1k98wkA1
This large study published in Lancet Infectious Diseases showed that full vaccination against COVID-19 cut the risk in half of long COVID-19 (long hauler syndrome) when breakthrough infection occur. Another strong reason to get vaccinated. https://t.co/xazVKkPIyD
— James E.K. Hildreth (@JamesEKHildreth) September 2, 2021
Metagenomic Sequencing as a Pathogen-Agnostic Clinical Diagnostic Tool for Infectious Diseases: a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studieshttps://t.co/odvU4v3r1b @ASMicrobiology pic.twitter.com/ca7Syfn1Wx
— JClinMicro EIC (@JClinMicro) August 30, 2021
The new Lancet Infectious Diseases study finds vaccination reduces risk of infection relative to unvaccinated who have not previously been infected (they don’t compare risk to unvaccinated with a previous infection) but ...https://t.co/lvDaARb53l
— David Paton (@cricketwyvern) September 2, 2021
The Lancet Infectious Diseases: Delta variant doubles risk of COVID-19 hospitalisation compared to alpha variant, new UK study confirms https://t.co/eYyP6hOreo
— Dr. Saskia Popescu (@SaskiaPopescu) August 30, 2021
Vaccinated people who contract Covid-19 have significantly lower odds of severe disease or hospitalisation than unvaccinated people, according to key findings of a study in the UK, published in The Lancet Infectious Diseases journal. https://t.co/5HVPCBO81I
— Times LIVE (@TimesLIVE) September 2, 2021
Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce | @NEJM https://t.co/j2iPqTDqiy The dramatic change in vaccine effectiveness from June to July is likely to be due to both the emergence of the delta variant and waning immunity over time.
— Carlos del Rio (@CarlosdelRio7) September 1, 2021
Conjugation inhibitors efficiently block plasmid transmission in two controlled natural environments, water microcosms and the mouse gut and indicate that they can be used to prevent the spread of antibiotic resistance. @mBioJournal https://t.co/HqvZWL9NRZ pic.twitter.com/MRveHFuqL3
— ASM (@ASMicrobiology) August 30, 2021
I agree with @US_FDA Acting Commissioner Dr. Janet Woodcock and @CDCDirector we need the scientists and not politicians to tell us when and who needs additional #Covidvaccine doses https://t.co/r95HiNn4y9
— Carlos del Rio (@CarlosdelRio7) September 3, 2021
Not only do vaccines work for humans,
— Umm Ismael Muslimah (@Ummismaelsf) August 31, 2021
They often work to save endangered species from infectious diseases.#GetVaccinatedNow#DemVoice1 #wtpBLUE#wtpEARTH https://t.co/NVGn6kH7cB
By showing dendritic cells partake in a “division of labor” when responding to a promising vaccine vector, a new study from @scisignal may inform the design of new #vaccines for infectious diseases and cancer. https://t.co/1WZy00jI3y pic.twitter.com/XV2nWdIwDu
— Science Magazine (@ScienceMagazine) August 31, 2021
What's next for mRNA technology? This article analyses the pipelines of mRNA companies and provides forecasts for the market in the main application areas: vaccines for infectious diseases (including COVID-19), therapeutic cancer vaccines and therapeutics https://t.co/aKlqpfiQxu pic.twitter.com/5HKuosjW4e
— Nature Reviews Drug Discovery (@NatRevDrugDisc) September 2, 2021
Covid-19 vaccines continue to offer strong protection against severe illness and hospitalization, according to research on more than 1,000,000 people published Wednesday in The Lancet Infectious Diseases. https://t.co/ue6m8kk6gP
— NBC News (@NBCNews) September 2, 2021
🆕💥💥systematic review #ofid
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 31, 2021
Lower Ct values (i.e., higher levels of viral RNA) correlating with increased disease severity & mortality ,those with Ct values <25 had a high risk of more severe disease and mortality than patients with Ct value >30 https://t.co/cywlRMS7qV
2 DAYS LEFT TO APPLY
— THET (@THETlinks) August 31, 2021
Health Partnerships are invited to apply for #CwPAMS grants to support #AntimicrobialStewardship in 8 Commonwealth countries: Ghana, Kenya, Malawi, Nigeria, Sierra Leone, Tanzania, Uganda & Zambia.
🖱️ https://t.co/4eSvm2x1p5@CW_Pharmacists @FlemingFund pic.twitter.com/ttMGlbQZ30
Major new article on the impact of #COVID19 on healthcare associated infections just published in @ICHEJournal:
— Mike Stevens (@Dr_Mike_Stevens) September 2, 2021
Major ⬆️ in CLABSI, CAUTI, VAE & MRSA bacteremia in 🇺🇸 #InfectionPrevention more important now than ever as we combat #Deltahttps://t.co/QNJVXRizMF@CDCgov pic.twitter.com/75RjXSUOUQ
New report focuses on how behavioural science can be used to support healthcare professionals to prescribe antibiotics in a way that aligns with antimicrobial stewardship strategy: https://t.co/u5wkpNzVtb
— Stop Superbugs (@TheUrgentNeed) September 2, 2021
The University of Colorado Infectious Diseases Division is recruiting for a Tenure Track Basic Science Faculty Position in Emerging Viruses 🧪🦠. Apply via link at bottom of our web page (Employment Opportunities, Faculty, 1st link):https://t.co/b3fEyXpVtl
— Eric Poeschla, MD (@EPoeschla) September 5, 2021
Estimated US Infection-and Vaccine-Induced SARS-CoV-2 Seroprevalence Based on Blood Donations,July 2020-May 2021 | Infectious Diseases | JAMA | JAMA Network
— Kris Held,MD (@kksheld) September 4, 2021
Also mentions “immunosenesence”in over 65 year olds. Further evidence for targeted vax,not mass vax https://t.co/d9fZcnyyjf
🆕💥 small single blinded RCT @InfectDis_Ther
— Antibiotic Steward 🆔🇵🇸 Bassam Ghanem (@ABsteward) August 30, 2021
Favipiravir appeared to shorten the time until clinical improvement by approximately 3 days in patients with moderate #COVID19 pneumonia presenting with SpO2 ≥ 94% as per the analysis planhttps://t.co/MY2VayY3Jm pic.twitter.com/A1zr3jVQkg
Want to come work with me, @carmenpenemase, and a host of amazing clinical pharmacists and physicians? @theprismahealth - Upstate is expanding our ID pharmacy team. Come see what #yeahTHATgreenville is all about: https://t.co/1LWqwP882z
— STennantrophomonas (@tennawitz) August 30, 2021
Created by Cameron Forbes. Last updated September 20, 2021 at 05:16 EST.